science and discovery | March 12, 2026

What to do if a PICC line is occluded?

What to do if a PICC line is occluded?

Try flushing the catheter with 10ml 0.9% saline. If the fluids still refuse to free-flow, then instil Urokinase into the catheter and leave for 60 minutes. If this fails, repeat the Urokinase instillation but this time leave it in the line for several hours or overnight.

Can a PICC become occluded?

Catheter occlusion is one of the most common complications associated with PICC insertion, affecting 1 in every 8 PICCs placed8. Occlusion may have important consequences for patients including inability to use the device, delays in tests or treatment, and sometimes the need to remove and replace the device.

What causes blood clot in PICC line?

Vascular Access through a PICC or Midline can cause Deep Vein Thrombosis (DVT) in the upper arm as a result of the catheter taking up and occupying space in the vein.

Can a PICC line cause DVT?

Although the insertion route of PICCs avoids complications such as pneumothorax or injury to the vessels of the neck and chest, PICCs are associated with important complications [1]. Principal among these is an increased risk of deep vein thrombosis (DVT) [2,3].

How do you fix IV occlusion?

What Should I Do If My Pump Reads “Down Occlusion”

  1. Check clamp on tubing and unclamp if clamped.
  2. Check tubing for any kinks or if patient is lying on tubing causing it to occlude.
  3. Make sure tubing is placed in pump correctly.
  4. Try to restart by pressing Pause/Yes to Resume/Run to Start.

What medication is used to unclog a PICC line?

Cathflo® Activase® (alteplase) is indicated for the restoration of function to central venous access devices as assessed by the ability to withdraw blood.

How do thrombotic occlusions develop?

Thrombotic occlusions result from the formation of a thrombus within, surrounding, or at the tip of the catheter. When introduced into the body, all catheters begin to accumulate fibrin.

What is pinch off syndrome?

Pinch-off syndrome (POS) occurs when a long-term central venous catheter is compressed between the clavicle and the first rib. The compression can cause transient obstruction of the catheter and may result in a tear or even complete transsection and embolization of the catheter.

How do you prevent blood clots in a PICC line?

Use your arm to do simple activities. This will help stop blood clots from forming in the PICC line. Have your first dressing changed within 48 hours of having the line inserted. Have the dressing changed at least every seven days.

How do you know if you have a blood clot from PICC line?

Blood clots swelling, redness or tenderness in the arm, chest area or up into the neck (on the same side as the PICC line) a swollen hand (on the same side as the PICC line) shortness of breath. tightness in your chest.

What are the complications of a PICC line?

PICC line complications can include:

  • Bleeding.
  • Nerve injury.
  • Irregular heartbeat.
  • Damage to veins in your arm.
  • Blood clots.
  • Infection.
  • A blocked or broken PICC line.

What does occlusion mean on IV?

An infusion pump is an electronic device used to control the administration of intravenous fluids to deliver measured amounts at careful and regulated rates. Occlusion is the interruption or ineffective therapy of infusion due to a blockage, momentary closure or obstruction of the passageway or blood vessel.